Dokumente
Suchschritt : FT=glucosamine AND FT=osteoarthritis
» Fenster schließen »

2/224 von 416 DIMDI: MEDLINE (ME60) © NLM

ND: | ME12186848
PMID: | 12186848
LR: | 20051116
CED: | 20020820
DCO: | 20021008
Autoren: | Freeze HH
Titel: | Sweet solution: sugars to the rescue.
Quelle: | The Journal of cell biology; VOL: 158 (4); p. 615-6 /20020819/
PM: | Print-Electronic
EPD: | 20020819
SU: | IM
Sprache: | English
CY: | United States
JID: | 0375356
ISSN: | 0021-9525
CO: | JCLBA3
Institution: | The Burnham Institute, La Jolla Cancer Research Center, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA. hudson@burnham.org
DT: | Comment; Journal Article; Review
RN: | 17
Schlagwörter
CT: | ANIMALS; CARRIER PROTEINS/genetics; COLITIS/drug therapy; COLITIS/etiology; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; FUCOSE/metabolism; FUCOSE/*therapeutic use; GLUCOSAMINE/*analogs & derivatives; GLUCOSAMINE/therapeutic use; GUANOSINE DIPHOSPHATE FUCOSE/*metabolism; HUMANS; LEUKOCYTE-ADHESION DEFICIENCY SYNDROME/*drug therapy; LEUKOCYTE-ADHESION DEFICIENCY SYNDROME/genetics; LEUKOCYTE-ADHESION DEFICIENCY SYNDROME/metabolism; LEUKOCYTE-ADHESION DEFICIENCY SYNDROME/physiopathology; MICE; MICE, KNOCKOUT; MONOSACCHARIDE TRANSPORT PROTEINS/*; MUTATION; OSTEOARTHRITIS/drug therapy; OSTEOARTHRITIS/etiology
CTG: | TIER; CARRIERPROTEINE/Genetik; KOLITIS/Arzneimitteltherapie; KOLITIS/Ätiologie; NAHRUNGSERGÄNZUNGSMITTEL; KRANKHEITSMODELLE, TIER; FUCOSE/Stoffwechsel; FUCOSE/*therapeutische Anwendung; GLUCOSAMIN/*Analoge & Derivate; GLUCOSAMIN/therapeutische Anwendung; GUANOSINDIPHOSPHAT-FUCOSE/*Stoffwechsel; MENSCH; LEUKOZYTEN-ADHÄSIONSMANGEL-SYNDROM/*Arzneimitteltherapie; LEUKOZYTEN-ADHÄSIONSMANGEL-SYNDROM/Genetik; LEUKOZYTEN-ADHÄSIONSMANGEL-SYNDROM/Stoffwechsel; LEUKOZYTEN-ADHÄSIONSMANGEL-SYNDROM/Pathophysiologie; MÄUSE; MÄUSE, KNOCKOUT-; MONOSACCHARID-TRANSPORTPROTEINE/*; MUTATION; OSTEOARTHROSE/Arzneimitteltherapie; OSTEOARTHROSE/Ätiologie
TE: | Carrier Proteins; Monosaccharide Transport Proteins; SLC35C1 protein, human; Guanosine Diphosphate Fucose/15839-70-0; Glucosamine/3416-24-8; Fucose/3713-31-3; N-acetylglucopyranosylamine/6983-36-4
CR: | 15839-70-0; 3416-24-8; 3713-31-3; 6983-36-4
NOTE: | Comment on: J Cell Biol. 2002 Aug 19;158(4):801-15; Ref.PMID: 12186857
AB: | Sugar pills are usually placebos, but Smith et al. (2002, this issue) use one to rescue designer mice unable to make GDP-Fucose. Dietary fucose enters a salvage pathway and spares the mice. Sound simple? Not so. Unknown genetic factors determine life or death.

» Volltext »
» Fenster schließen »