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Suchschritt : FT=glucosamine AND FT=osteoarthritis
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2/204 von 416 DIMDI: MEDLINE (ME60) © NLM

ND: | ME12562155
PMID: | 12562155
LR: | 20051116
CED: | 20030203
DCO: | 20030220
Autoren: | Morelli V; Naquin C; Weaver V
Titel: | Alternative therapies for traditional disease states: osteoarthritis.
Quelle: | American family physician; VOL: 67 (2); p. 339-44 /20030115/
PM: | Print
SU: | AIM IM
Sprache: | English
CY: | United States
JID: | 1272646
ISSN: | 0002-838X
CO: | AFPYA
Institution: | Family Practice Residency Program, Louisiana State University Health Sciences Center, Kenner, Louisiana 70065, USA.
DT: | Journal Article; Review
RN: | 41
Schlagwörter
CT: | CHONDROITIN SULFATES/therapeutic use; COMPLEMENTARY THERAPIES/*; DRUG THERAPY, COMBINATION; GLUCOSAMINE/therapeutic use; HUMANS; OSTEOARTHRITIS/*therapy; S-ADENOSYLMETHIONINE/therapeutic use
CTG: | CHONDROITINSULFATE/therapeutische Anwendung; KOMPLEMENTÄRE THERAPIEVERFAHREN/*; ARZNEIMITTEL-KOMBINATIONSTHERAPIE; GLUCOSAMIN/therapeutische Anwendung; MENSCH; OSTEOARTHROSE/*Therapie; S-ADENOSYLMETHIONIN/therapeutische Anwendung
TE: | S-Adenosylmethionine/29908-03-0; Glucosamine/3416-24-8; Chondroitin Sulfates/9007-28-7
CR: | 29908-03-0; 3416-24-8; 9007-28-7
NOTE: | Comment in: Am Fam Physician. 2003 Nov 1;68(9):1713; author reply 1713; Ref.PMID: 14620592
AB: | Americans spend more on natural remedies for osteoarthritis than for any other medical condition. In treating osteoarthritis, glucosamine and chondroitin sulfate, two of the molecular building blocks found in articular cartilage, are the most commonly used alternative supplements. In randomized trials of variable quality, these compounds show efficacy in reducing symptoms, but neither has been shown to arrest progression of the disease or regenerate damaged cartilage. Although few clinical trials on S-adenosylmethionine exist, preliminary evidence indicates that it relieves pain to a degree similar to that of nonsteroidal anti-inflammatory drugs but with fewer side effects. Clinical trials of dimethyl sulfoxide offer conflicting results. Neither ginger nor cetyl myristoleate has proven clinical usefulness.

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