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Suchschritt : FT=glucosamine AND FT=osteoarthritis
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2/164 von 416 DIMDI: MEDLINE (ME60) © NLM

ND: | ME14713401
PMID: | 14713401
LR: | 20051116
CED: | 20040109
DCO: | 20040426
Autoren: | Zerkak D; Dougados M
Titel: | The use of glucosamine therapy in osteoarthritis.
Quelle: | Current rheumatology reports; VOL: 6 (1); p. 41-5 /200402/
PM: | Print
SU: | IM
Sprache: | English
CY: | United States
JID: | 100888970
ISSN: | 1523-3774
Institution: | Rheumatology B Department, René Descartes University, AP-HP Cochin Hospital, 27 rue du Faubourg Saint Jacques, Paris 75014, France.
DT: | Journal Article; Review
RN: | 40
Schlagwörter
CT: | CARTILAGE, ARTICULAR/*drug effects; GLUCOSAMINE/pharmacology; GLUCOSAMINE/*therapeutic use; HUMANS; OSTEOARTHRITIS/*drug therapy; RANDOMIZED CONTROLLED TRIALS; RANGE OF MOTION, ARTICULAR; TREATMENT OUTCOME
CTG: | KNORPEL, GELENK-/*Arzneimittelwirkungen; GLUCOSAMIN/Pharmakologie; GLUCOSAMIN/*therapeutische Anwendung; MENSCH; OSTEOARTHROSE/*Arzneimitteltherapie; RANDOMISIERTE KONTROLLIERTE STUDIEN; BEREICH DER GELENKBEWEGLICHKEIT; BEHANDLUNGSERGEBNIS
TE: | Glucosamine/3416-24-8
CR: | 3416-24-8
AB: | Glucosamine products have been used extensively for the management of pain in osteoarthritis. This paper reviews the most recent clinical and experimental studies regarding its efficacy and safety. Although clinical trials include methodologic flaws and publication bias, glucosamine is likely an effective therapy for the symptomatic management of osteoarthritis. In turn, definite proof for chondromodulating effect requires well-conducted clinical trials. In North America, glucosamine is an over-the-counter dietary supplement and preparations made by different manufacturers may vary. There is also a need to standardize this therapy and allow practitioners to give patients suitable advice. An ongoing long-term clinical trial in the US will possibly permit to investigate the clinical relevance of these results and give appropriate recommendations.

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