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ND: | ME12382365
PMID: | 12382365
LR: | 20061115
CED: | 20021017
DCO: | 20030103
Autoren: | Bijlsma JW
Titel: | Glucosamine en chondroïtinezwavelzuur als mogelijke behandeling van artrose. Glucosamine and chondroitin sulfate as a possible treatment for osteoarthritis
Quelle: | Nederlands tijdschrift voor geneeskunde; VOL: 146 (39); p. 1819-23 /20020928/
PM: | Print
SU: | IM
Sprache: | Dutch
CY: | Netherlands
JID: | 0400770
ISSN: | 0028-2162
CO: | NETJAN
Institution: | Universitair Medisch Centrum, afd. Reumatologie & Klinische Immunologie, Postbus 85.500, 3508 GA Utrecht.
DT: | English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Review
RN: | 25
Schlagwörter
CT: | ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL/therapeutic use; CHONDROITIN SULFATES/adverse effects; CHONDROITIN SULFATES/*therapeutic use; DIETARY SUPPLEMENTS; GLUCOSAMINE/adverse effects; GLUCOSAMINE/*therapeutic use; HUMANS; OSTEOARTHRITIS/*drug therapy; TREATMENT OUTCOME
CTG: | ANTIPHLOGISTIKA, NICHTSTEROIDALE/therapeutische Anwendung; CHONDROITINSULFATE/unerwünschte Nebenwirkungen; CHONDROITINSULFATE/*therapeutische Anwendung; NAHRUNGSERGÄNZUNGSMITTEL; GLUCOSAMIN/unerwünschte Nebenwirkungen; GLUCOSAMIN/*therapeutische Anwendung; MENSCH; OSTEOARTHROSE/*Arzneimitteltherapie; BEHANDLUNGSERGEBNIS
TE: | Anti-Inflammatory Agents, Non-Steroidal; Glucosamine/3416-24-8; Chondroitin Sulfates/9007-28-7
CR: | 3416-24-8; 9007-28-7
AB: | The nutritional supplements glucosamine and chondroitine sulphate are widely used in the treatment of osteoarthritis. In published studies, glucosamine used in a dosage of 1.5 gram daily is, after a period of 2 to 4 weeks, just as effective as low doses of NSAIDs in alleviating pain. Chondroitine sulphate has been less well investigated. There are indications that it affects the symptoms of osteoarthritis, even though this effect only occurs after a longer period of time. The side effects for both substances are minor. A disease-modifying effect (defined as delay of radiological progression of osteoarthritis) has not been proven.

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