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Suchschritt : FT=glucosamine AND FT=osteoarthritis
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ND: | ME12926646
PMID: | 12926646
LR: | 20051116
CED: | 20030820
DCO: | 20040204
Autoren: | Reginster JY; Bruyere O; Henrotin Y
Titel: | New perspectives in the management of osteoarthritis. structure modification: facts or fantasy?
Quelle: | The Journal of rheumatology. Supplement; VOL: 67; p. 14-20 /200308/
PM: | Print
SU: | IM
Sprache: | English
CY: | Canada
JID: | 7806058
ISSN: | 0380-0903
CO: | JRSUDX
Institution: | Bone and Cartilage Metabolism Research Unit, University of Liège, CHU Centre-Ville, Policliniques L. Brull, Liège, Belgium. jyreginster@ulg.ac.be
DT: | Journal Article; Review
RN: | 56
Schlagwörter
CT: | ANTHRAQUINONES/metabolism; ANTHRAQUINONES/pharmacology; ANTHRAQUINONES/therapeutic use; ANTI-INFLAMMATORY AGENTS/*pharmacology; ANTI-INFLAMMATORY AGENTS/*therapeutic use; CHONDROITIN SULFATES/metabolism; CHONDROITIN SULFATES/pharmacology; CHONDROITIN SULFATES/therapeutic use; DRUGS, NON-PRESCRIPTION/standards; DRUGS, NON-PRESCRIPTION/therapeutic use; GLUCOSAMINE/metabolism; GLUCOSAMINE/pharmacology; GLUCOSAMINE/therapeutic use; HUMANS; OSTEOARTHRITIS/*drug therapy; OSTEOARTHRITIS/pathology; OSTEOARTHRITIS/physiopathology; PLANT OILS/metabolism; PLANT OILS/pharmacology; PLANT OILS/therapeutic use
CTG: | ANTHRACHINONE/Stoffwechsel; ANTHRACHINONE/Pharmakologie; ANTHRACHINONE/therapeutische Anwendung; ANTIPHLOGISTIKA/*Pharmakologie; ANTIPHLOGISTIKA/*therapeutische Anwendung; CHONDROITINSULFATE/Stoffwechsel; CHONDROITINSULFATE/Pharmakologie; CHONDROITINSULFATE/therapeutische Anwendung; ARZNEIMITTEL, NICHT VERSCHREIBUNGSPFLICHTIGE/Standard; ARZNEIMITTEL, NICHT VERSCHREIBUNGSPFLICHTIGE/therapeutische Anwendung; GLUCOSAMIN/Stoffwechsel; GLUCOSAMIN/Pharmakologie; GLUCOSAMIN/therapeutische Anwendung; MENSCH; OSTEOARTHROSE/*Arzneimitteltherapie; OSTEOARTHROSE/Pathologie; OSTEOARTHROSE/Pathophysiologie; PFLANZENÖLE/Stoffwechsel; PFLANZENÖLE/Pharmakologie; PFLANZENÖLE/therapeutische Anwendung
TE: | Anthraquinones; Anti-Inflammatory Agents; Drugs, Non-Prescription; Plant Oils; diacetylrhein/13739-02-1; Glucosamine/3416-24-8; Chondroitin Sulfates/9007-28-7
CR: | 13739-02-1; 3416-24-8; 9007-28-7
AB: | Several entities have been carefully investigated for the symptomatic and structural management of osteoarthritis (OA). The most compelling evidence of a potential for inhibiting the structural progression of OA has been obtained with glucosamine sulfate, while some preliminary results also suggest that other compounds could be used in the same indication. At any rate, several medications have clearly demonstrated a symptomatic action, mainly in OA of the lower limbs, including pain relief and improvement of functional disability. An important issue is that all conclusive studies with such chemical entities resulted from the use of prescription medicines and not over-the-counter or nutriceutical supplements.

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