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Suchschritt : FT=glucosamine AND FT=osteoarthritis
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ND: | ME03382265
PMID: | 3382265
LR: | 20041117
CED: | 19880721
DCO: | 19880721
Autoren: | Krajícková J; Macek J
Titel: | Urinary proteoglycan degradation product excretion in patients with rheumatoid arthritis and osteoarthritis.
Quelle: | Annals of the rheumatic diseases; VOL: 47 (6); p. 468-71 /198806/
PM: | Print
SU: | IM
Sprache: | English
CY: | ENGLAND
JID: | 0372355
ISSN: | 0003-4967
CO: | ARDIAO
Institution: | Research Institute of Rheumatic Diseases, Praha, Czechoslovakia.
DT: | Journal Article
Schlagwörter
CT: | ARTHRITIS, RHEUMATOID/*urine; FEMALE; GALACTOSAMINE/urine; GLUCOSAMINE/urine; GLYCOSAMINOGLYCANS/*urine; HUMANS; MALE; MANNOSE/urine; MIDDLE AGED; OSTEOARTHRITIS/*urine; PROTEOGLYCANS/metabolism; URONIC ACIDS/urine
CTG: | ARTHRITIS, RHEUMATOIDE/*Harn; WEIBLICH; GALACTOSAMIN/Harn; GLUCOSAMIN/Harn; GLYCOSAMINO-GLYCANE/*Harn; MENSCH; MÄNNLICH; MANNOSE/Harn; MENSCHEN IM MITTLEREN LEBENSALTER; OSTEOARTHROSE/*Harn; PROTEOGLYCANE/Stoffwechsel; URONSÄUREN/Harn
TE: | Glycosaminoglycans; Proteoglycans; Uronic Acids; Mannose/31103-86-3; Glucosamine/3416-24-8; Galactosamine/7535-00-4
CR: | 31103-86-3; 3416-24-8; 7535-00-4
AB: | The excretion of sugar components of glycosaminoglycans in the urine was investigated in 19 healthy controls, 27 patients with rheumatoid arthritis, and 24 with osteoarthritis. Both groups of patients excreted significantly more glucosamine, galactosamine, and mannose than the controls. The total uronic acid excretion, also, was higher in the two groups than in the healthy subjects. The possibility of using this method for the long term follow up of rheumatoid arthritis and osteoarthritis and the response to treatment is discussed.

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