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Suchschritt : FT=glucosamine AND FT=osteoarthritis
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2/170 von 416 DIMDI: MEDLINE (ME60) © NLM

ND: | ME14963912
PMID: | 14963912
LR: | 20061115
CED: | 20040213
DCO: | 20040722
Autoren: | Lu F; Guo H
Titel: | Study on the role of glucosamine hydrochloride in the pathogenesis of osteoarthritis
Quelle: | Wei sheng yan jiu = Journal of hygiene research; VOL: 32 (6); p. 594-7 /200311/
PM: | Print
SU: | IM
Sprache: | Chinese
CY: | China
JID: | 9426367
ISSN: | 1000-8020
CO: | WEYAEM
Institution: | School of Public Health, Fudan University, Shanghai 200032, China.
DT: | English Abstract; Journal Article
Schlagwörter
CT: | ANIMALS; ARTHRITIS, EXPERIMENTAL/etiology; ARTHRITIS, EXPERIMENTAL/pathology; GLUCOSAMINE/*physiology; GLUCOSAMINE/therapeutic use; GRANULOMA/pathology; MALE; OSTEOARTHRITIS/*etiology; OSTEOARTHRITIS/prevention & control; RATS; RATS, SPRAGUE-DAWLEY
CTG: | TIER; ARTHRITIS, EXPERIMENTELLE/Ätiologie; ARTHRITIS, EXPERIMENTELLE/Pathologie; GLUCOSAMIN/*Physiologie; GLUCOSAMIN/therapeutische Anwendung; GRANULOM/Pathologie; MÄNNLICH; OSTEOARTHROSE/*Ätiologie; OSTEOARTHROSE/Verhütung & Bekämpfung; RATTUS; RATTEN, SPRAGUE-DAWLEY-
TE: | Glucosamine/3416-24-8
CR: | 3416-24-8
AB: | The role of glucosamine hydrochloride in the pathogenesis of osteoarthritis in animal models of sponge granuloma, Kaolin arthritiaand and adjuant arthritis was studied. The results showed that glucosamine hydrochloride inhibited granulation, delayed immunoreactivity, immunological-reative arthritis in daily doses of 0.25-0.75 g/kg BW orally and vascular oozing, tissue swelling and cell isolating in daily doses of 0.5-1.5 g/kg BW orally, indicating that glucosamine hydrochloride might have a preventive and theraputic effect on osteoarthritis.

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