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Suchschritt : FT=glucosamine AND FT=osteoarthritis
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2/363 von 416    DIMDI: MEDLINE (ME60) © NLM
ND: ME08767975
PMID: 8767975
LR: 20061115
CED: 19961023
DCO: 19961023
Autoren: Giordano N; Nardi P; Senesi M; Palumbo F; Battisti E; Gonnelli S; Franci B; Campagna MS; Gennari C
Titel: Efficacia e tollerabilità della glucosamina solfato nel trattamento della gonartrosi.
The efficacy and safety of glucosamine sulfate in the treatment of gonarthritis
Quelle: La Clinica terapeutica; VOL: 147 (3); p. 99-105 /199603/
PM: Print
SU: IM
Sprache: Italian
CY: ITALY
JID: 0372604
ISSN: 0009-9074
CO: CLTEA4
Institution: Istituto di Patologia Speciale Medica, Università degli Studi di Siena.
DT: Comparative Study; English Abstract; Journal Article
Schlagwörter
CT: ADULT; AGED; AMINO ACIDS/*therapeutic use; AMINO SUGARS/*therapeutic use; DRUG THERAPY, COMBINATION; DRUG TOLERANCE/*; FEMALE; GLUCOSAMINE/*therapeutic use; HUMANS; MIDDLE AGED; OSTEOARTHRITIS/*drug therapy; TREATMENT OUTCOME
CTG: ERWACHSENER; ALTE MENSCHEN; AMINOSÄUREN/*therapeutische Anwendung; AMINOZUCKER/*therapeutische Anwendung; ARZNEIMITTEL-KOMBINATIONSTHERAPIE; ARZNEIMITTELTOLERANZ/*; WEIBLICH; GLUCOSAMIN/*therapeutische Anwendung; MENSCH; MENSCHEN IM MITTLEREN LEBENSALTER; OSTEOARTHROSE/*Arzneimitteltherapie; BEHANDLUNGSERGEBNIS
TE: Amino Acids; Amino Sugars; Glucosamine/3416-24-8; pyridinoline/63800-01-1
CR: 3416-24-8; 63800-01-1
AB: This study was performed to evaluate the therapeutic efficacy and tolerability of glucosamine sulfate in patients with gonarthritis. During the 12-month study period, the signs and symptoms of the disease were evaluated, as well as the dosage of the urinary pyridinoline. In this trial, we demonstrated that glucosamine sulfate has a chondroprotective activity, which was significant after the first 3 months of therapy. Moreover, this study showed that the side effects due to glucosamine sulfate were mild to moderate and did not require discontinuation of the drug.
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